![]() Signs and symptoms depend on which arteries are affected. Some people may have signs and symptoms of illness. ![]() They have a medical emergency, such as a heart attack or stroke. Many people don’t know that they have a disease until Signs, Symptoms, and ComplicationsĪtherosclerosis usually does not cause signs and symptoms until the artery is severely narrowed or completely blocked. Eventually, the area of the plate may rupture (break open). ![]() Over time, the plate hardens and narrows the arteries. Plaque may begin to build up where the arteries have been damaged.
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